Skip links

info@visionofresearch.ae

14th Floor, Dubai Science Park South Tower - Al Barsha South - Dubai - UAE

+971 425 44824

Start a Project

Academic & Research Platforms

University & Discovery-Oriented Services

1.End-to-End Research Project Design

2.Scientific Positioning & Topic Strategy

3.Hypothesis & Research Question Engineering

4.Study Methodology & Experimental Workflow

5.Statistical Design & Power Analysis

6.Biomarker, Gene & Target Strategy

7.Assay Selection & Validation Planning

8.Translational & Regulatory Alignment

9.Risk Management, Quality & Reproducibility

10.Data Analysis, Reporting & Scientific Support

1.Neurology & Neuroscience

2.Metabolic & Endocrine Models

3.Cardiovascular & Stroke Models

4.Reproductive & Fertility Models

5.Immunology & Inflammation

6.Liver & Kidney Disease Models

7.Gastrointestinal & Microbiome

8.Regenerative & Wound Healing

9.Toxicology & Safety Models

10.Ocular & Retinal Disease Models

11.Respiratory Disease Models

12.Musculoskeletal & Arthritis Models

13.Urology & Renal Function Models

14.Ocular & Retinal Disease Models

1.Learning, Memory & Cognition

2.Anxiety & Stress Behavior Assessment

3.Depression & Motivation Behavior

4.Pain & Nociception Assessment

5.Motor Function & Coordination

6.Sensorimotor Integration & Reflexes

7.Seizure & Epilepsy-Related Behavior

8.Sleep & Circadian Rhythm

9.Social Behavior & Communication

10.Reward, Addiction & Motivation

11.Fatigue & Exercise Capacity

12.Gastrointestinal & Feeding Behavior

13.Metabolic & Energy Balance

14.Urinary & Bladder Function

15.Cardiovascular Function & Stroke

16.Regenerative Functional Readouts

17.General Activity, Locomotion

Clinical Monitoring

  • General Appearance & Condition
  • Behavior & Stress Indicators
  • Grooming & Coat Condition
  • Respiratory Patterns & Function
  • Toxicity & Distress Signs
  • Body Weight & Growth Monitoring
  • Food Intake & Nutritional Status
  • Hydration & Fluid Balance

Hematological & Biochemical

  • Complete Blood Count (CBC)
  • Clinical Biochemistry Panels
  • Electrolyte

1.Gene Expression (PCR-based)

2.Nucleic Acid Extraction & Synthesis

3.Design of Nucleotide Primer Sequences

4.PCR & Advanced Molecular Analysis 

5.DNA & RNA Quantification

6.Agarose Gel Electrophoresis Performance

7.Epigenetic and DNA Methylation Assays

8.Transcriptomic and RNA-Seq Analysis

9.CRISPR-Based Genetic Validation Assays

10.Protein Expression (WB)

11.Biomarker Quantification (ELISA)

1.Cell Line Preparation & Treatment

2.Cell Viability, Proliferation & Cytotoxicity

3.Cell Migration, Invasion & Angiogenesis

4.Flow Cytometry & Cell Fate Analysis

5.Oxidative Stress & Drug Response

6.Cell Labeling, Tracking & Differentiation

7.Imaging & Microscopy

8.Organ-on-a-Chip & Advanced In-Vitro Models

9.Advanced Cellular & Molecular Platforms

10.Protein, Antibody & Omics-Related Services

1.IHC, IF & TUNEL assay

2.Fluorescent Staining Techniques

3.Specialized Staining Techniques

  • Structural and Morphological Tissue
  • Fibrosis and Extracellular Matrix
  • Neurodegeneration & Neural Integrity
  • Metabolic Changes & Lipid Accumulation
  • Mineralization and Calcification
  • Vascular Structure and Elastic Fibers
  • Inflammation & Immune Response
  • Vital Function & Cellular Differentiation
  • Microbiological Staining Techniques
  • Microscopic Imaging Platforms

1.Quantitative Analysis & Reporting

2.Tissue Evaluation & Analysis

3.Qualitative & Semi-Quantitative Analysis

4.Scientific & Regulatory Support

1.Isolation, Culture & Identification

2.Biochemical & Phenotypic Characterization

3.Antimicrobial & Antibiotic Evaluation

4.Mechanism of Action & Antimicrobial Resistance

5.Applied & Industrial Microbiology Services

1.Plant Extraction

2.Plant Extract Drying

3.Essential Oil Synthesis

4.Nanoparticle Synthesis

5.Exosome Isolation

Visionofresearch

Efficacy & Specialty Assay Modules

Efficacy Specialty Modules

Advanced efficacy modules provide direct, quantitative, and mechanism-based evidence proving that a drug produces its intended therapeutic effect. Safety establishes whether a drug causes adverse effects, while efficacy confirms its ability to deliver meaningful therapeutic benefit.

These modules are designed to generate quantitative, imaging, and analytical data confirming treatment response, provide documentation for funding, patents, publications, and pharmaceutical partnerships, and define or validate the mechanism of action, such as metabolic effects, pancreatic repair, anti-inflammatory pathways, neuroprotection, or anticancer activity. As with safety modules, not all efficacy modules are required; selection is mechanism-driven, and typically, one to two modules are sufficient to meet these objectives.

General physiological data from early stages describe what happens to the animal, but do not prove disease improvement. Early-stage studies focus on understanding the animal’s response, whereas efficacy modules systematically assess whether the drug meaningfully improved the disease and elucidate its underlying mechanism of action. These modules:

  • Therapeutic Outcome Focus: Measuring disease-specific improvements, not general signs.
  • Multi-Level Analysis: Evaluating drug effects at cellular, tissue, and molecular levels.
  • Signal Specificity: Distinguishing true pharmacological effects from nonspecific changes.
  • Tailored Integration: Modules, tissues, and assays uniquely combined per disease model.
Send a Message

Request a Call Back

    Veterinary Industry Innovation

    1

    Inflammatory Pathway Assessment

    The Inflammatory Axis is a foundational component of our preclinical analysis, designed to evaluate the role of systemic and localized inflammation in diseases such as cancer, stroke, diabetes, and neurodegenerative disorders. By quantifying key cytokines (e.g., IL‑6, TNF‑α, IL‑1β, IL‑10) and immune cell markers such as CD68, Iba1, and GFAP, we provide detailed insights into a drug’s impact on pro‑inflammatory signaling, immune cell activity, and NF‑κB pathway activation. This axis is essential for developing targeted anti‑inflammatory therapies and understanding how drug candidates modulate immune responses across a range of inflammatory-driven conditions.

    Key Biomarkers & Methods:

    • Cytokine profiling panels (IL‑6, TNF‑α, IL‑1β, IL‑10)
    • Macrophage & microglia markers (CD68, Iba1, GFAP)
    • NF‑κB activation assays
    Learn more
    Veterinary Industry Innovation

    2

    Oxidative Stress & Antioxidant Profiling

    The Oxidative Stress Axis quantifies the imbalance between reactive oxygen species (ROS) and antioxidant capacity, a key driver of tissue damage in liver disease, kidney injury, neurological disorders, and metabolic syndromes. Through assays measuring MDA, SOD, GSH/GSSG ratios, and ROS levels, we evaluate a drug’s ability to mitigate oxidative damage and enhance cellular antioxidant defenses. This axis provides critical data for therapies targeting neurodegeneration, organ injury, cardiovascular disease, and metabolic dysfunction, where oxidative stress significantly contributes to disease progression.

    Key Biomarkers & Methods:

    • Lipid peroxidation marker (MDA)
    • Antioxidant enzyme activity (SOD)
    • Redox status (GSH/GSSG ratio) and ROS quantification assays
    Learn more
    Veterinary Industry Innovation

    3

    Metabolic Function & Hormonal Analysis

    Our Metabolic Axis offers comprehensive profiling for metabolic disorders such as diabetes, obesity, NAFLD/NASH, and endocrine dysfunction. By integrating oral glucose tolerance tests (OGTT), insulin tolerance tests (ITT), lipid metabolism panels, and hormonal assays (insulin, leptin, adiponectin, cortisol), we assess how a drug influences energy homeostasis, insulin sensitivity, and lipid metabolism. This axis is crucial for evaluating drug candidates in metabolic disease models and supports the development of therapies that restore metabolic balance.

    • Key Biomarkers & Methods:
    • Glucose regulation tests (OGTT, ITT)
    • Lipid metabolism profiling
    • Hormonal assays (insulin, leptin, adiponectin, cortisol)
    Learn more
    Veterinary Industry Innovation

    4

    Fibrosis & Extracellular Matrix Evaluation

    The Fibrosis & ECM Remodeling Axis focuses on quantifying fibrotic progression and extracellular matrix (ECM) changes in chronic conditions such as liver fibrosis, kidney disease, pulmonary fibrosis, heart failure, and gastrointestinal fibrosis. Using histological staining (Masson’s trichrome, Sirius Red) and molecular markers including α‑SMA and collagen I/III, we determine whether a therapeutic intervention can prevent, halt, or reverse fibrotic tissue remodeling. This axis provides essential structural and molecular endpoints for anti‑fibrotic drug development.

    Key Biomarkers & Methods:

    • Histological stains (Masson’s Trichrome, Sirius Red)
    • Fibrosis markers (α‑SMA, collagen I/III)
    Learn more
    Veterinary Industry Innovation

    5

    Apoptosis & Cellular Proliferation Monitoring

    The Apoptosis & Cell Turnover Axis measures the balance between programmed cell death and cellular proliferation in oncology, neurodegeneration, liver injury, kidney disease, and cardiac damage. Through assays such as caspase‑3 activity, Ki‑67 proliferation index, and TUNEL staining, we evaluate whether a drug promotes cell survival, inhibits abnormal proliferation, or modulates apoptotic pathways. This axis delivers critical insights into a drug’s impact on cellular fate, supporting therapeutic strategies for cancer, neuroprotection, and organ repair.

    Key Biomarkers & Methods:

    • Caspase‑3 activity assay
    • Ki‑67 proliferation marker
    • TUNEL assay for apoptosis detection
    Learn more
    Veterinary Industry Innovation

    6

    Vascular Function & Angiogenesis Studies

    The Vascular & Endothelial Axis evaluates drug effects on blood vessel formation, stability, and endothelial health in cardiovascular disease, stroke, cancer, and tissue regeneration models. By measuring CD31 (endothelial marker), VEGF expression, and performing angiogenesis and vascular integrity assays, we determine a compound’s ability to modulate vascular growth, barrier function, and endothelial signaling. This axis is vital for developing therapies targeting vascular dysfunction, ischemia, tumor angiogenesis, and inflammatory vascular injury.

    Key Biomarkers & Methods:

    • Endothelial marker (CD31)
    • VEGF expression and secretion analysis
    • Angiogenesis and vascular integrity assays
    Learn more
    Veterinary Industry Innovation

    7

    Immune Response & Activation Profiling

    The Immune Activation Axis maps adaptive immune responses critical for cancer immunotherapy, autoimmune disease, vaccine development, and systemic inflammatory disorders. Using T‑cell subset profiling and comprehensive flow cytometry panels, we track drug‑induced changes in immune cell populations, activation states, and cytokine profiles. This axis enables the development of precise immunomodulatory strategies, providing a detailed understanding of how drug candidates shape cellular immunity and immune‑driven therapeutic outcomes.

    Key Biomarkers & Methods:

    • T‑cell subset profiling
    • Immune phenotyping via flow cytometry panels
    Learn more